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Curriculum
Vitae
2006
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Jennifer D Wallace
(Neuroendocrine Scientist)
Griffith University Learning Centre
GULC Annex, Logan Hospital
177 Armstrong & Loganlea Road
Meadowbrook
Queensland 4131
Australia.
Telephone: 07 3342 2797 (Home,
MessageBank and Fax)
0412 667 533 (mobile), 07 3299 9596
(office)
e-mail:
aghdaware@optusnet.com.au
Name:
Jennifer D Wallace
Address: Brisbane, Queensland,
Australia.
Telephone: 07 3342 2797 (H), 0412 667 533 (m), 07 3399 9596 (w)
Fax: 07 3342 2797
E-mail:
aghdaware@optusnet.com.au
D.O.B: 10th December 1963
Place of Birth: England, United Kingdom
Residence Status: Permanent Resident of Australia since 1990.
Director of General Surgery
Senior Transplant Surgeon
Princess Alexandra Hospital
Ipswich Road, Woolloongabba,
Brisbane, Queensland 4102
Telephone: 07 3240 2767
Fax: 07 3240 7011
Email: daryl_wall@health.qld.gov.au
Director, Neuroendocrine Research Unit
Consultant, Endocrinology and Internal Medicine
Professor of Medicine, Logan Campus
School of Medicine
GRIFFITH UNIVERSITY
Logan Hospital
Meadowbrook Qld 4131 Australia
Telephone 07 3299 8155
Fax 07 3299 8887
Email r.jackson@griffith.edu.au
OR:
rick_jackson@health.qld.gov.au
Neurosurgeon
Associate Professor, University of Queensland.
Postal Address:
Alexandra
201 Wickham Terrace
Brisbane, Qld 4000
Tel: 07 3839 3393
Mobile: 0412 022 282
Fax: 07 3832 2005
E-mail: leighatkinson@optusnet.com.au
|
2006 |
Research
Scholar/Fellow |
University of Queensland
Southern Clinical School
& Griffith Learning Centre
Griffith University Logan
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2000 to end 2005 |
Senior Scientist and
Clinical Research Director
Metabolic Research Unit |
Department of Diabetes and Endocrinology
& University of Queensland
Department of Medicine
Princess Alexandra Hospital
Brisbane, Australia.
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1998 & 1999 |
Senior Research Scientist |
UQ Dpt Med.
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1996 & 1997 |
Joint appointment:
Senior Research Scientist
& Research Associate |
UQ Dpt Med
Dpt Med
St Thomas’ Hospital London
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1995 |
Senior Research Scientist. |
UQ Dpt Med
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1992 to end 1994 |
Research Scientist. |
UQ Dpt Med
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1991 |
Senior Research Assistant. |
UQ Dpt Med
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1990 |
Research Assistant. |
UQ Dpt Med
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1988 to end 1989 |
Senior Physiological
Measurement Technician |
Dpt Med
St Thomas’
Hospital London
|
2006: Currently writing up PhD on: The Detection of Growth Hormone (GH) Abuse
by Elite Athletes: Studies On The Effect of Exercise, GH Treatment and GH Withdrawal In Human Male Athletes.
1998: National Assessment in Respiratory Physiology (UK), 1988.
1987: B.Sc. (Hons.), University of London, UK. Aug. 1987, (2.2).(Honours
research project on Physiological Correlates of Stress received Ist Class award).
(12 weeks, 1 night per week, personal development and
mentorship training).
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Clinical Respiratory Physiology: Royal Postgraduate Medical school, Hammersmith Hospital,
London, 1988.
I have addressed these criteria below under the headings of:
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Major Themes/Areas of Research In Which I Am Involved
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Major Research Developments, Achievements and Outcomes:
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Service Within The Hospital and University
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External Service
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Consultative And Related Outside Work
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Adults with growth-hormone deficiency.
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Adults with Acromegaly.
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Normal adults including aged populations.
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Veteran athletes.
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Adults with Chronic Liver Disease.
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Adults post liver transplantation.
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Highly trained athletes.
I have worked in the Department of Medicine for 15
years researching growth hormone (GH) regulation, physiology and pathophysiology in normal subjects, ageing athletes, adults with growth hormone deficiency,
adults with Acromegaly and adults with chronic liver disease; and most recently young male athletes as part of a large European based project funded by the
International Olympic Committee and the European Union, (US$3,000,000), with the objective of developing a GH detection methodology for the 2000 Olympics. I
have recently completed the clinical aspect of a significant project as co-principal investigator and coordinator of the $355,584 NHMRC grant: Regulation and
effect of the growth hormone, IGF-I, and IGF-Binding protein response to acute exercise, during which I extensively explored thermoregulation and intermediary
metabolism, in growth hormone deficient adults; I have recently been co-investigator on two projects with Acromegalic adults, one which compares medical vs
surgical treatment in Acromegaly, and the other which investigates the efficacy of treatment with a novel somatostatin analogue. I have also recently
supervised a neuro-surgical registrar to develop a rat model of Acromegaly and to pursue our ideas of developing a novel treatment of pituitary tumours with a
radio-labelled neuropeptide in collaboration with the Australian Nuclear Science and Technology Organization. On the basis of my publications in the area of GH
physiology and GH doping, I was contacted by and am presently collaborating with the Australian Proteomic Analytical Facility in Sydney, in a grant application
to the United States Anti Doping Agency for US$760,000. This application has been reviewed and a request for supporting preliminary data was made. I have
performed some human experimentation to allow APAF to perform analytical work as preliminary data, and would like to create the opportunity to perform more
human research work in Brisbane if funding becomes available.
In partnership with Ross Cuneo I have dedicated the last 15 years to
performing carefully conducted experimenter driven clinical research, and some of the highlights and major achievements have been:
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Performed some of the world’s first absorption profiles of recombinant human growth hormone in human adults in the 1980’s.
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Set
up the Metabolic Research Unit at Princess Alexandra Hospital in 1990 for purposes of conducting experimenter driven clinical research into physiology and
pathophysiology of GH regulation. Metabolic testing facilities included respiratory gas analysis, exercise testing, ECG assessment, body composition analysis
(including anthropometry, swept frequency bioelectrical impedance and energy expenditure with D20), 24 hour hormone profile determination,
nutritional and metabolic status determination and estimation of resting metabolic rate. More recently methods have been established for investigation of
thermoregulation such as: infra-red photography, detection of sweat gland activation and density with hydrophobic polymer application, measurement of sweat
gland activation and secretion rate with ventilated capsule capacitance hygrometry, skin blood flow detection and measurement of core temperature with rectal
probes.
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Single-handedly set up state of the art exercise physiology laboratory in St Thomas Hospital London with sponsorship by the IOC. Performed all validation work
and wrote and implemented human physiology protocols. Designed conducted and supervised studies from conception to pubication in highly cited, internationally
recognised journals.
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Contributed intellectually and practically to empirical research to demonstrate efficacy and safety of GH treatment in GH deficient adults world-wide. Major
contribution to the establishment in the world literature of an essential role for Growth Hormone in adult physiology, in the fields of body composition,
exercise performance, cardiac function, lipid metabolism, and psychological function. Contributed significantly to 10 year follow up of GH treatment in GH
deficient adults which is considered as a landmark publication along with earlier treatment studies.
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Major contributor to industry applications to Therapeutic Goods Administration resulting in authorization of prescription of GH for treatment of GH deficiency
in adults and also recent application to government for PBS subsidization.
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One
of the first in the world to develop the concept that dysregulated GH/insulin-like growth factor-l axis may contribute to the catabolic process of cirrhosis,
and to treat patients with supraphysiologic doses of GH with the aim of overcoming that GH resistance. Probably first in the world to perform a detailed
treatment trial, but not first published due to manpower limitations. (This was my 2nd PhD project).
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First to characterize the GH/IGF axis and define the endogenous secretory pattern of GH in patients with liver cirrhosis both before and after liver
transplantation.
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First in the world literature to discover the profound effect of GH on antinatriuresis and contribution to clinically significant ascites and oedema in patients
with cirrhosis: leading to potential novel therapeutic strategies in the treatment of resistant ascites.
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First in the world to study the effect of strenuous exercise on the diurnal, endogenous GH secretory profiles in adult humans.
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Significant efforts to explore the concept that some of the detrimental effects of ageing are mediated by reductions in endogenous GH production, as a result of
diminution of physical activity. (This was my masters’ project which got turned into a PhD project!).
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Significant contribution to the efforts to develop a program to detect GH and IGF-1 abuse in Olympic athletes: studies funded by the European Union and the
International Olympic Committee. World-first systematic study of the effects of exercise, GH administration and exercise, and GH withdrawal on potential
markers of GH abuse in athletes. Studies led to new understandings of the effect of the GH/IGF axis on normal exercise physiology. (This was my 3rd
PhD project!)
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Significant contribution to establishing a rat model of Acromegaly, and investigating the development of radio-labeled neuro-peptides in the treatment of
Acromegaly. (This was my second post-doc project!).
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Significant contribution to working protocols for the investigation of novel therapeutic approaches for industry developed pharmaceutical treatment of
Acromegaly.
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Design
and execution of Innovative and highly technical systematic study of thermoregulation and regulation of GH/IGF system in growth hormone deficiency before and
after growth hormone treatment. (This was my first post-doc project!)
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Developing a world-wide reputation for innovative and carefully conducted experimenter driven research.
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Significant contribution to establishing an Australia-wide registry for Acromegaly.
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Developing an international reputation for expertise in GH neuroendocrine physiology and sport.
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Establishing collaboration on a global scale in a diverse range of clinically relevant fields.
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To
have succeeded in obtaining funding from a wide range of granting bodies both internal and external, national and international including the coveted NH$MRC
award!
The wide range of roles I have performed in my career as a researcher
over the years, both in active research and supervision, have given me a great breadth of practical experience in management of both students and co-workers.
I have contributed widely to Problem Based Learning in the Graduate
Medical Course as outlined in the response to selection criteria above.
I have provided mentorship both officially and to the wider student and
staff community in both the hospital and university for many years and the practical effectiveness of my skills will be evident from the references provided.
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Professional Service
(including clinical activities and leadership, etc) |
Description of Role |
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National Health and Medical Research Council
Local organizing committee member for 2nd Joint GH-IGF
Symposium 18-22 April 2004, Cairns, Australia
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Grant Net Reviewer
Working together with The Growth Hormone Research Society and The
International Society for IGF Research to stage an International Conference. |
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Clinical Endocrinology |
Reviewer |
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The Journal of Clinical Endocrinology and Metabolism |
Reviewer |
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Archives of Pediatrics & Adolescent Medicine |
Reviewer |
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European Journal of Endocrinology |
Reviewer |
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Treatments in Endocrinology |
Reviewer |
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Journal of Hepatology |
Reviewer |
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Medicine and Science in Sports and Exercise |
Reviewer |
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Journal of Bone and Mineral Research |
Reviewer |
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Medical Science Monitor |
Reviewer |
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Australian & New Zealand Acromegaly Registry (ANZAR) |
Founding member of working party to develop a tumour registry,
assess cost: effectiveness of treatment, and develop prospective treatment trials. |
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Project Description
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Genotropin / Somavert Advisory Board, Pfizer Australia
(to consider the scientific and marketing issues for Genotropin in
adult GH deficiency as well as in Acromegaly. |
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Advisor to Novo Nordisk Australia
Submission to TGA for the Indication of rhGH to treat adults with
GHD. |
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Wallace
JD and Cuneo RC. Growth Hormone and Sport. The Endocrine System In
Sports and Exercise, Olympic Encyclopaedia of Sports Medicine Volume XI,
Edited by Kraemer W and Rogol A, Blackwell Publishing, 2005.
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Cuneo RC and Wallace
JD. Skeletal and Cardiac Muscle in Adults with Growth Hormone
Deficiency. In: Frontiers of Hormone Research, vol. 33, Growth Hormone
Deficiency in Adults, pp 121-145, Edited by J.O.L. Jorgensen and J.S.
Christiansen, series editor A.B. Grossman, Karger 2005.
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Sönksen PH, Wallace JD,
Cuneo RC. Growth hormone abuse in elite athletes. in “Drug Abuse
Handbook”, S.B. Karch, M.D. (ED), CRC Press, Boca Raton, Florida, 1997. pp
690-710
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Olson SL, Wallace JD,
Atkinson L and Cuneo RC. Benign Intracranial Hypertention Associated With
Acormegaly. The Endocrinologist 2005; 15 (3), 1-4.
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Wallace JD,
Abbott-Johnson WJ, Crawford DHG, Barnard R, Potter J, Cuneo RC. GH
treatment in adults with chronic liver disease: a randomised, double-blind,
placebo-controlled, cross over study. Journal of Clinical Endocrinology and
Metabolism 2002, 87(6): 2751-2759.
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Wallace JD, Cuneo
RC, Bidlingmaier M, Lundberg P-A, Carlsson L, Boguszewski CL, Hay J, Healy
M-L, Napoli R, Dall R, Rosen T, Strasburger CJ. The response of molecular
isoforms of growth hormone (GH) to acute exercise in trained adult males. J
Clin Endocrinol Metabol 2001; 86(1):200-206.
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Wallace JD, Cuneo
RC, Bidlingmaier M, Lundberg P-A, Carlsson L, Boguszewski CL, Hay J,
Boroujerdi M, Cittadini A, Dall R, Rosen T, Strasburger CJ Changes in
non-22-kilodalton (kDa) isoforms of growth hormone (GH) after administration
of 22kDa recombinant human GH in trained adult males. J Clin Endocrinol
Metabol 2001; 86(4):1731-37.
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Cuneo RC
and Wallace JD. Adult growth hormone deficiency: what does the
newest hormone replacement therapy do? Current Therapeutics 2001;
42(12/1):43-47.
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Wallace JD, Cuneo
RC. Growth hormone and sport. Int. Growth Monitor, 2000, 10(2):2-6.
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Wallace JD, Cuneo
RC. Growth hormone abuse in athletes: a review. The Endocrinologist, 2000,
10:175-184.
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Wallace JD, Cuneo
RC, Lundberg PA, Rosen T, Jorgensen JOL, Longobardi S, Keay N, Sacca L,
Christiansen JS, Bengtsson BA, Sonksen P. Responses of markers of bone and
collagen turnover to exercise, growth hormone (GH administration and GH
withdrawal in trained adult males.) J Clin Endocrinol Metabol 2000,
85(1):124-133.
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Dall R, Longobardi S,
Ehrnborg C et al on behalf of the GH2000 Study Group (Includes Wallace JD
and Cuneo RC). The effect of four weeks of supra-physiological growth
hormone administration on the IGF-axis in women and men. J Clin Endocrinol
Metabol 2000, 85(11):4193-4200.
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Longobardi S, Keay N,
Ehrnborg C et al on behalf of GH2000 Study Group (Includes Wallace JD
and Cuneo RC). Growth hormone (GH) effects on bone and collagen turnover in
healthy adults and its potential as a marker of GH abuse in sports: a double
blind, placebo-controlled study. J Clin Endocrinol Metabol 2000,
85(4):1505-12.
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Wallace JD, Cuneo
RC, Baxter R, Orskov H, Keay N, Pentecost C, Dall R, Rosen T, Jorgensen JO,
Cittadini A, Longobardi S, Sacca L, Christiansen JS, Bengtsson BA, Sonksen
PH. Responses of the growth hormone (GH) and insulin-like growth factor
axis to exercise, GH administration and GH withdrawal in trained adult
males: a potential test for GH abuse in sport. J Clin Endocrinol Metabol
1999, 84(10):3591-3601.
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Meeking DR,
Wallace JD, Cuneo RC, Forsling RC, Russell-Jones DL.
Exercised-induced GH secretion in enhanced by the oral ingestion of
melatonin in healthy adult male subjects. European Journal of Endocrinology
1999, 141(1):22-6.
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Gibney J, Wallace JD
Spinks T, Schnorr L, Ranicar A Cuneo RC, Lockhart S, Burnand KG, Salomon F,
Sonksen PH, rusell-Jones D. The effects of 10 years of recombinant human
growth hormone in adult growth hormone deficient patients. J Clin
Endocrinol Metabol 1999, 84(8):2596-2602.
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Cuneo RC, Judd S,
Wallace JD, Perry-Keene D, Burger H, Lim-Tio S, Strauss B, Stockigt J,
Topliss D, Alford F, Hew L, Bode H, Conway A, Handelsman, D, Dunn S, Boyages
S, Cheung W, Hurley D. The Australian Multi-centre Trial of Growth Hormone
Treatment in Growth Hormone Deficient Adults. J Clin Endocrinol Metabol
1998; 83:1:107-116.
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Cuneo RC,
Hickman P, Wallace JD, The BT, Ward G, Veldhuis JD, & Waters MJ.
Altered endogenous growth hormone secretory kinetics and diurnal GH-binding
protein profiles in adults with chronic liver disease. Clin Endocrinol.
1995; 43: 265-275.
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Cuneo RC &
Wallace JD. Growth hormone, insulin-like growth factors and sport.
Endocrinol Metabolism. 1994; 1: 3-13.
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Crawford DHG, Halliday JW,
Cooksley WGE, Murphy TL, Golding SM, Wallace JD, Cuneo RC, Lynch SV,
Strong RJ, & Powell LW. The distribution of body water in patients with
cirrhosis: The effect of liver transplantation. Hepatology 1993; 17:
1016-1021
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Pratt EJ,
Wallace JD, Cuneo RC.
Reduced Sweating Before and After Vigorous Exercise In Growth
Hormone Deficient Adults. Proceedings of the 2nd International GH-IGF
Symposium, April 2004, Cairns Australia.
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Pratt
EJ, Wallace JD, Cuneo RC.
Prevalence of growth hormone deficiency in a tertiary referal
centre. Proceedings of the 44th Annual Scientific Meeting, Endocrine Society
of Australia, Gold Coast, September 2001, #423.
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*Wallace JD,
Cuneo RC, Bidlingmaier M, Rosen T, Lundberg PA, Carlsson L, Hay J, Sonksen
PH, Sacca L, Dall, Strasburger. Detection of exogenous 22kDa growth hormone
(GH) by suppression of the proportion of non-22-kDa isoforms in exercising,
trained adult males. Proceedings of 11th International Congress of
Endocrinology, Sydney October 2000, p.194.
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*Wallace JD,
Cuneo RC. Misuse of growth hormone.
Novo Nordisk
Satellite Symposium to ICE 2000.
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*Wallace
JD, Cuneo RC, Bidlingmaier M, Sonksen PH, Sacca L, Christiansen JS,
Lundberg PA, Strasburger CJ.
The response of molecular isoforms of growth hormone (GH) to acute
exercise in trained adult males.
Growth Hormone & IGF Research, 2000, 10(3):134.
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*Wallace JD,
Cuneo RC. Developments on the GH2000 project in the lead up to the 2000
Olympics. Drugs in Sport, 1999 vol. 10: 11.
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Ehrnborg C,
Lange K, Baxter R, et al on behalf of the GH2000 Study Group
(includes
J.D.Wallace).
GH/IGF-1 and related parameters in elite athletes- a longitudinal study.
Proceedings US Endocrine Society’s 81st Annual Meeting, 1999. P.574.
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Healy ML, Dall
R, Ehnrborg C et al on behalf of the GH2000 Study Group
(includes
J.D.Wallace).
GH/IGF-1 and related parameters in elite athletes – a post competition,
cross-sectional study. Proceedings US Endocrine Society’s 81st Annual
Meeting, 1999. P.575.
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Longobardi S,
Keay N, Ehrnborg C et al on behalf of the GH2000 Study Group
(includes
J.D.Wallace).
Growth hormone (GH) effects on bone and collagen turnover in healthy
adults and its potential usefulness in the detection of GH sport abuse. A
double blind, placebo-controlled study. Proceedings US Endocrine
Society’s 81st Annual Meeting, 1999. P.394.
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Dall
R, Longobardi S, Ehrnborg C, et al on behalf of the GH2000 Study Group
(includes J.D.Wallace).
IGF related markers of supraphysiological exogenous GH exposure in 102 adult
healthy young adults. Proceedings US Endocrine Society’s 81st Annual
Meeting, 1999. P.81.
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Boroujerdi MA,
Dall R, Keay N, et al on behalf of the GH2000 Study Group
(includes
J.D.Wallace).
Stimulation of growth hormone dependant markers during and following growth
hormone treatment. Proceedings US Endocrine Society’s 81st Annual Meeting,
1999. P.397.
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*Wallace
JD,
Cuneo RC. Development of a detection system for the use of growth hormone in
sport. Proceedings Endocrine Society of Australia’s 42nd Annual Meeting,
1999. P51.
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*Wallace JD,
Wu Z, Bidlingmaier M, on behalf of the GH2000 Study Group. Molecular
isoforms of growth hormone (GH) in the detection of exogenous GH
administration in athletes. Proceedings Endocrine Society of Australia’s
42nd Annual Meeting, 1999. P 66.
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Cuneo
RC, Wallace JD. The use of growth hormone as a drug of abuse in
sport. Proceedings Endocrine Society of Australia’s 42nd Annual Meeting,
1999. P50.
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Gibney J,
Wallace JD, Spinks T, Burnand K, Cuneo R, Salomon F, Sönksen P and
Russell-Jones D. The effects of 10 years of recombinant Human Growth
Hormone in adult growth hormone deficient patients. Journal of
Endocrinology March 1998, vol 156, supplement, #P191.
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Gibney J,
Wallace JD, Spinks T, Burnand K, Cuneo R, Salomon F, Sönksen P and
Russell-Jones D. The effects of 10 years of recombinant Human Growth
Hormone in adult growth hormone deficient patients. Proceedings of the
European Congress of Endocrinology, Seville, Spain, May 1998.
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Gibney J,
Wallace JD, Spinks T, Burnand K, Cuneo R, Salomon F, Sonksen P and
Russell-Jones D. 10 years of replacement with recombinant human growth
hormone in adult growth hormone deficient patients. The 80th Annual
Meeting of the Endocrine Society, New Orleans, June 1998.
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P.Burman on
behalf of the The Australian Adult Growth Hormone Study Group (includes
J.D.Wallace). The effects of body composition and serum IGF-1 during
treatment with genotropin in adult patients with multiple pituitary hormone
deficiencies as compared with patients with isolated GHD. US Endocrine
Society Meeting, New Orleans, June 1998.
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P.Burman, Anni
Sietnieks, Patrik Ohagen on behalf of the Study Group for Adult GHD
(includes J.D.Wallace). Predicting the response of growth hormone
treatment experience in 709 adults with GH deficiency. US Endocrine
Society Meeting, New Orleans, June 1998.
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Ross C Cuneo and
Jennifer D Wallace. Doping in sport, an overview. The Clinical
Biochemist Reviews 1998;19:(iii):70, Proceedings of the Australasian
Association of Clinical Biochemists, 36th Annual Scientific Conference,
Brisbane, August 1998.
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*Jennifer
Wallace, Ross C Cuneo, Robert Baxter, Thord Rosén, B-Å Bengtsson, R.
Dall, Jens-Otto Jorgensen, Hans Orskof, Antonio Cittadini, Salvatore
Longobardi, Luigi Sacca, Claire Pentecost, Marie-Louise Healey, Peter
Sönksen. Endocrine markers of growth hormone abuse in sport.
Proceedings of the 41st Annual Scientific Meeting, Endocrine Society of
Australia, Perth, August 1998, volume 41, p.55, abstract #7.
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Ross C. Cuneo,
Jennifer D Wallace, Thord Rosén, Per-Arne Lundberg, Beng-Åke
Bengtsson, R Dall, Jens O.L. Jorgensen, Jens S Christiansen, Antonio
Cittadini, Salvatore Longobardi, Luigi Sacca, Claire Pentecost, Nicola Keay,
Peter Sönksen. Use of bone markers to detect growth hormone abuse in
sport. Proceedings of the 41st Annual Scientific Meeting, Endocrine
Society of Australia, Perth, August 1998, volume 41, p.55, abstract
#8.
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Catherine S
Choong, Jennifer D Wallace, David Cowley, Ross C Cuneo. Prostate
specific antigen levels following GH treatment in GH deficient adults.
Proceedings of the 41st Annual Scientific Meeting, Endocrine Society of
Australia, Perth, August 1998, volume 41, p.74, abstract #45.
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*JD Wallace,
RC Cuneo, R Baxter, T Rosén, B-Å Bengtsson, R Dall, JO Jorgensen, C
Pentecost, ML Healey, A Cittadini, S Longobardi. Detection of growth
hormone abuse in athletes. Growth Hormone & IGF Research Vol 8:4:329,
August 1998,abstract #O66 of the Growth Hormone Research Society
Conference, San Francisco, 3-7 September 1998.
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JD Wallace,
RC Cuneo, T Rosén, B-Å Bengtsson, P-A Lundberg, R Dall,JS Christiansen, C
Pentecost, N Keay, A Cittadini, S Longobardi. Bone Markers and Growth
Hormone (GH) Abuse in Athletes. Growth Hormone & IGF Research Vol
8:4:348, August 1998,abstract #P71 of the Growth Hormone Research
Society Conference, San Francisco, 3-7 September 1998.
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ML Healy, J
Gibney, J Wallace, P Sönksen & D Russell-Jones. A comparison of
three methods of assessing body composition in growth hormone-deficient
adults. Growth Hormone & IGF Research Vol 8:4:345, August 1998,abstract
#P63 of the Growth Hormone Research Society Conference, San Francisco, 3-7
September 1998.
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ML Healy, J
Gibney, J Wallace, R Cuneo, P Sönksen, D Russell-Jones. The
effects of 10 years of recombinant human growth hormone ( Psychological
Well-Being). Growth Hormone & IGF Research Vol 8:4:349, August 1998,
abstract #P75 of the Growth Hormone Research Society Conference, San
Francisco, 3-7 September 1998.
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J Gibney, J
Wallace, A Wierzibicki, R Cuneo, F Salomon, P Sönksen & D Russell-Jones.
The effects of 10 years of recombinant human growth hormone (Lipid
Status). Growth Hormone & IGF Research Vol 8:4:349, August 1998,
abstract #P76 of the Growth Hormone Research Society Conference, San
Francisco, 3-7 September 1998.
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*Jennifer D
Wallace and Ross C Cuneo. Endocrine markers of growth hormone abuse
in sport: Invited lecture (NB same title but different content to ESA
Abstract). Proceedings of the Sports Medicine Australia Conference, Perth,
October 1998.
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Cuneo
RC, Alford F, Burger H, Handelsman D, and the Adult GH Deficiency Study
Group
(includes J.D.Wallace).
Responsiveness to GH treatment in adults with GH deficiency: comparison
of those patients with normal vs sub-normal pre-treatment serum IGF-I.
Endocrine Society of Australia’s annual scientific meeting, Canberra 1997,
abstract #106.
-
Burman P,
Sietnieks A, Öhagen P, and The Study Group for Adult GHD
(includes
J.D.Wallace).
Patients with isolated GH deficiency have a similar responsiveness to GH
treatment as patients with multiple pituitary hormone deficiencies.
European Neuroendocrine Association meeting, Sept 1997, Marseilles,
France. Published in supplement to “Annales d’Endocrinologie”.
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Meeking DR,
Wallace JD, Cuneo RC, Mullan G, Sharma S, Sawyer A, Forsling M,
Russell-Jones D. Exercise-induced growth hormone secretion is enhanced by
the oral ingestion of melatonin in healthy adult male subjects. Clin
Endocrinol 1997;. A25.
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*Wallace JD,
Cuneo RC, Alford F, Handelsman D, Burger H and the Adult GH Deficiency Study
Group. Prediction of response to GH treatment in adults with GH
deficiency: comparison of those patients with normal vs sub-normal
pre-treatment serum IGF-I. Proceedings of the 24th International
Symposium of Growth Hormone and Growth Factors in Endocrinology and
Metabolism, Antwerp, Belgium 1997.
-
P.Burman, Anni
Sietnieks, Patrik Öhagen and The Study Group for Adult GHD
(includes
J.D.Wallace).
The responsiveness to growth hormone treatment is similar in patients
with isolated growth hormone deficiency and those with multiple pituitary
hormone deficiencies. Proceedings of the 24th International Symposium of
Growth Hormone and Growth Factors in Endocrinology and Metabolism Antwerp,
Belgium, 1997.
-
P.Burman, Anni
Sietnieks, Patrik Öhagen and The Study Group for Adult GHD
(includes
J.D.Wallace).
The effects of body composition and serum IGF-I during treatment with
genotropin in adult patients with multiple pituitary hormone deficiencies as
compared with patients with isolated GHD. Poster abstract presented at (i)
The 8th Meeting of the European Neuroendocrine Association, September
1997, Marseilles, France, and (ii) the 24th International Symposium on
Growth Hormone and Growth Factors in Endocrinology and Metabolism Antwerp,
Belgium, 1997.
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*Wallace JD,
Cuneo RC, Abbott W. Growth hormone treatment in adults with liver
cirrhosis: effects on body composition and metabolism. 10th
International Congress of Endocrinology, San Francisco, June 1996:
#OR37-6.
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Australian
Multicentre Adult GHD study Group: Burger H, Alford F, Bode H, Boyages S,
Cheung W, Conway A, Cuneo R, Handelsman D, Hew L, Hurley D, Judd S, Lim-Tio
S, Perry-Keene D, Stogkigt J, Strauss B, Topliss D, Wallace J.
Impact of growth hormone therapy on cardiovascular risk factors and body
composition in adult growth hormone deficiency. Proc Endo Soc Australia
1995; 38: 129.
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*Wallace JD,
Cuneo RC, Yandle T, Espiner EA.
Growth hormone
(GH) treatment in adults with GH deficiency: effects on distribution of body
water and volume regulatory hormones. Proc Endo Soc Australia 1995; 38: 130.
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*Wallace JD,
Cuneo RC. Growth hormone treatment in adults with liver cirrhosis.
Proc Aust Parenteral and Enteral Nutrition Society. 1995; 40.
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Cuneo RC,
Hickman P, Wallace JD, Teh BT, Ward G, Veldhuis JD, Waters MJ.
Diurnal growth hormone (GH) and GH‑binding protein profiles in adults with
chronic liver disease. Endo Soc Australia Proc 1993; 36: 21.
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Non Refereed Publications and Original Contributions:
A Meta-Analysis and Review of Responses to GH Treatment in GH Deficient Adults
Ross C Cuneo and Jennifer D Wallace
Commissioned by Novo Nordisk 2001
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Special Report to the
International Olympic Committee and the European Union:
GH-2000 A Methodology for the Detection of
Doping with Growth Hormone and Related Substances,
A Biomed 2 Project, Contract Number: BMH4
CT950678.
Prof. R.Baxter, Prof. B. A. Bengtsson, Dr E.
Bassett, Prof P Brown, Prof J.S. Christiansen, Dr R. Cuneo, Dr L Fryklund, Dr
A-M Kappelgaard, Dr M. Kenward, Prince Alexander De Morode, Dr L Rivier, Prof.
L. Sacca, Dr M Saugy, Prof. P. Sonksen, Dr C. Strassburger, J.D. Wallace.
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Community Service |
Description of Role |
|
Advocate for the Growth Hormone Treatment of Growth Hormone
Deficient Adults |
Clinical researcher and advisor to industry on scientific and
clinical grounds and attempting to influence government policy with respect to subsidising treatment.
Providing HOPE to sufferers and carers “hope protects us from
despair”.
|
|
Advocate
for Drug Free Arena for Sports Competition |
Research, education and awareness raising. |
|
Brisbane Marathon
and Road Runners Club |
Committee Member
/ paramedical support |
|
Recreational Athlete |
Raising money for charity and promoting healthy attitudes to
exercise and community participation. |
|
Australian Paralympians |
Fundraiser |
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Queensland Bushwalking Club |
Adventure Leader, providing adventure, personal growth and
community. |
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New Holland Baroque |
Sponsor/ musician host |
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